Measuring hexokinase activity in
cellular aging. Bone marrow
mesenchymal stem cells (MSC)
were cultured in vitro. Early and
late passage MSC were harvested
for enzyme assay. The study
shows that hexokinase activity is
increased upon repeated cell
passages in vitro.
Welcome to BMR
- Streamlining Laboratory Medicine -
Biomedical Research Service & Clinical
Application is affiliated with the School of
Medicine and Biomedical Sciences,
University at Buffalo. The center produces
high-quality, cost-effective research and
diagnostic reagents for the broad life
science and clinical communities, and
promotes collaborative translational
research. Please send your inquiry to:
Dr. Techung Lee
Department of Biochemistry
& Department of Biomedical Engineering
University at Buffalo
Tel: (716) 829-3106
Fatty acid oxidation in the heart.
Mice were fed methionine-choline
deficient diet (MCDD) for 14 weeks.
Heart tissues were homogenized
and FAO activities were assayed by
the FAO Assay kit.
Biomedical Research Service
& Clinical Application
Measuring L-lactate levels in
culture media. The assay reveals
that lactate production by the Bcl-2
expressor is reduced compared to
the parental HEK293 cells.
Here are some of the
pharmaceutical and biotech
companies we have proudly
served over the years:
Discovering IMPDH inhibitors.
HeLa cells were treated with
DMSO (control) and 10 uM
mycophenolic acid (MPA) for 24
hours, following which cells were
harvested and IMPDH activity was
measured using the IMPDH assay
Discovering inhibitor of MMP2/9.
Prinomastat, a potent MMP
inhibitor, reduces the activity of
MMP2/9 by ~70% at 2.5 nM using
the assay kit.